Skip to main content

Clinical oncology

Section edited by: Prof Serigne Magueye Gueye and Prof Jan Vermorken. 

The clinical oncology section represents an opportunity to share experiences and information among worldwide oncologists and to identify and develop diagnostic as well as therapeutic protocols, which are globally valid in the current global village. Potential topics include, but are not limited to: epidemiology, pathology and pathogenesis of cancers and clinical studies

Page 1 of 5

  1. T cell epitopes are polypeptide fragments presented to T cell receptors by MHC molecules encoded by human leukocyte antigen (HLA) genes after antigen-presenting cell processing, which is the basis for the stud...

    Authors: Hongchao Cai, Yaning Feng, Peiwen Fan, Yuping Guo, Gulina Kuerban, Cheng Chang, Xuan Yao, Yanchun Peng and Ruozheng Wang

    Citation: Infectious Agents and Cancer 2021 16:61

    Content type: Research Article

    Published on:

  2. We evaluated several biological indicators based on inflammation and/or nutritional status, such as systemic immune-inflammation index (SII), early warning score (ANDC) and prognostic nutritional index (PNI) i...

    Authors: Muge Bilge, Isil Kibar Akilli, Ekrem Bilal Karaayvaz, Aylia Yesilova and Kadriye Kart Yasar

    Citation: Infectious Agents and Cancer 2021 16:60

    Content type: Research Article

    Published on:

  3. While the epidemiologic association between hepatitis B virus (HBV) infection and diffuse large B-cell lymphoma (DLBCL) is established, little is known about the pathological characteristics and outcome of DLB...

    Authors: Dao-guang Chen, Gang Chen, Chang Wang, Long-feng Ke, Hui Wu, Hong-ming He, Yu Yang and Yan-ping Chen

    Citation: Infectious Agents and Cancer 2021 16:57

    Content type: Research Article

    Published on:

  4. Head and neck squamous cell carcinoma (HNSCC) is the 6th most common malignant cancer type worldwide. Radiosensitivity has been shown to be significantly increased in patients with human papillomavirus (HPV)-p...

    Authors: Dan Long, Li Xu, Zeyi Deng, Dandan Guo, Yangchun Zhang, Zhaohui Liu and Chunlin Zhang

    Citation: Infectious Agents and Cancer 2021 16:56

    Content type: Research Article

    Published on:

  5. This article provides an overview of diagnostic evaluation and ablation treatment assessment in Hepatocellular Carcinoma (HCC). Only studies, in the English language from January 2010 to January 202, evaluatin...

    Authors: Vincenza Granata, Roberta Grassi, Roberta Fusco, Andrea Belli, Carmen Cutolo, Silvia Pradella, Giulia Grazzini, Michelearcangelo La Porta, Maria Chiara Brunese, Federica De Muzio, Alessandro Ottaiano, Antonio Avallone, Francesco Izzo and Antonella Petrillo

    Citation: Infectious Agents and Cancer 2021 16:53

    Content type: Review

    Published on:

  6. High-risk human papillomavirus (HR-HPV) are responsible for cervical cancer (CC) which represents the second most prevalent gynecological cancer among Tunisian women. Preventive strategies against CC are based...

    Authors: Rahima Bel Haj Rhouma, Monia Ardhaoui, Emna El Fehri, Asma Marzougui, Thalja Laassili, Ikram Guizani, Med Samir Boubaker and Emna Ennaifer

    Citation: Infectious Agents and Cancer 2021 16:52

    Content type: Research Article

    Published on:

  7. Human T-lymphotropic virus 1 (HTLV-1) infection may lead to the development of Adult T-cell leukemia/lymphoma (ATLL). To further elucidate the pathophysiology of this aggressive CD4+ T-cell malignancy, we have...

    Authors: Shahrzad Shadabi, Nargess Delrish, Mehdi Norouzi, Maryam Ehteshami, Fariba Habibian-Sezavar, Samira Pourrezaei, Mobina Madihi, Mohammadreza Ostadali, Foruhar Akhgar, Ali Shayeghpour, Cobra Razavi Pashabayg, Sepehr Aghajanian, Sayed-Hamidreza Mozhgani and Seyed-Mohammad Jazayeri

    Citation: Infectious Agents and Cancer 2021 16:49

    Content type: Research Article

    Published on:

  8. Circular RNA circRHOBTB3 has been characterized as a tumor suppressor in gastric cancer, while its role in hepatocellular carcinoma (HCC) is unknown. This study was carried out to analyze the role of circRHOBT...

    Authors: Gang Hu, Shusen Zhai, Sheng Yu, Zhen Huang and Ran Gao

    Citation: Infectious Agents and Cancer 2021 16:48

    Content type: Research Article

    Published on:

  9. Despite extensive molecular epidemiological studies, the prevalence and characteristics of Mouse Mammary Tumor Virus-Like Virus (MMTV-LV) in Chinese women breast cancer are still unclear. Besides, the prevalen...

    Authors: Fa-liang Wang, Xiao-li Zhang, Ming Yang, Jun Lin, Yong-fang Yue, Ya-dan Li, Xian Wang, Qiang Shu and Hong-chuan Jin

    Citation: Infectious Agents and Cancer 2021 16:47

    Content type: Research Article

    Published on:

  10. Having a 30-year follow-up of a cohort of women tested for HPV is a unique opportunity to further study long-term risk of CIN3+. The study objective was to compare HPV status at baseline with the risk of CIN3+...

    Authors: Marit Østlyngen Riibe, Sveinung Wergeland Sørbye, Gunnar Skov Simonsen, Arnfinn Sundsfjord, Josef Ekgren and Jan Martin Maltau

    Citation: Infectious Agents and Cancer 2021 16:46

    Content type: Research Article

    Published on:

  11. In December 2019 an outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 was first observed in Wuhan, China. The virus has spread rapidly throughout the world creating a pandemic scenario. Several risk ...

    Authors: Lorena Cardillo, Claudio de Martinis, Maurizio Viscardi, Claudia Esposito, Emanuela Sannino, Gabriella Lucibelli, Antonio Limone, Stefania Pellino, Rosa Anastasio, Roberta Pellicanò, Loredana Baldi, Giorgio Galiero and Giovanna Fusco

    Citation: Infectious Agents and Cancer 2021 16:45

    Content type: Research Article

    Published on:

  12. Epigenetic mechanisms are hypothesized to contribute substantially to the progression of cervical intraepithelial neoplasia (CIN) to cervical cancer, although empirical data are limited.

    Authors: Claire Bosire, Adriana C. Vidal, Jennifer S. Smith, Dereje Jima, Zhiqing Huang, David Skaar, Fidel Valea, Rex Bentley, Margaret Gradison, Kimberly S. H. Yarnall, Anne Ford, Francine Overcash, Susan K. Murphy and Cathrine Hoyo

    Citation: Infectious Agents and Cancer 2021 16:42

    Content type: Research Article

    Published on:

  13. Radiomics is an emerging field and has a keen interest, especially in the oncology field. The process of a radiomics study consists of lesion segmentation, feature extraction, consistency analysis of features,...

    Authors: Vincenza Granata, Roberta Fusco, Maria Luisa Barretta, Carmine Picone, Antonio Avallone, Andrea Belli, Renato Patrone, Marilina Ferrante, Diletta Cozzi, Roberta Grassi, Roberto Grassi, Francesco Izzo and Antonella Petrillo

    Citation: Infectious Agents and Cancer 2021 16:39

    Content type: Research Article

    Published on:

  14. Currently 12 human polyomaviruses (HPyVs) have been identified, 6 of which have been associated with human diseases, including cancer. The discovery of the Merkel cell polyomavirus and its role in the etiopath...

    Authors: Faisal Klufah, Ghalib Mobaraki, Dan Liu, Raed A. Alharbi, Anna Kordelia Kurz, Ernst Jan M. Speel, Véronique Winnepenninckx and Axel zur Hausen

    Citation: Infectious Agents and Cancer 2021 16:35

    Content type: Review

    Published on:

  15. Since December 2019, the global burden of the COVID-19 pandemic has increased rapidly and has impacted nearly every country in the world, affecting those who are elderly or with underlying comorbidities or imm...

    Authors: Giuseppe Pannone, Vito Carlo Alberto Caponio, Ilenia Sara De Stefano, Maria Antonietta Ramunno, Mario Meccariello, Alessio Agostinone, Maria Carmela Pedicillo, Giuseppe Troiano, Khrystyna Zhurakivska, Tommaso Cassano, Maria Eleonora Bizzoca, Silvana Papagerakis, Franco Maria Buonaguro, Shailesh Advani and Lorenzo Lo Muzio

    Citation: Infectious Agents and Cancer 2021 16:34

    Content type: Review

    Published on:

  16. Cancer of the uterine cervix remains a main public health problem in Sub-Saharan Africa. About two-thirds of patients with cervical cancer were diagnosed at late stage with contributing factors of out-of-pocke...

    Authors: Mulugeta Wassie and Beletech Fentie

    Citation: Infectious Agents and Cancer 2021 16:30

    Content type: Research Article

    Published on:

  17. Human papillomavirus (HPV) is a sexually transmitted infection common among men and women of reproductive age worldwide. HPV viruses are associated with epithelial lesions and cancers. HPV infections have been...

    Authors: Maria Isaguliants, Stepan Krasnyak, Olga Smirnova, Vincenza Colonna, Oleg Apolikhin and Franco M. Buonaguro

    Citation: Infectious Agents and Cancer 2021 16:29

    Content type: Review

    Published on:

  18. Early diagnosis can significantly improve treatment outcomes for hepatocellular carcinoma (HCC) patients. Currently, the dosage of serum alpha fetoprotein (AFP) is widely used in the diagnosis of HCC, but this...

    Authors: Jian Zhou, Yue Zhu, Yi Li, Kun Liu, Fei He, Sihuan Xu, Xin Li, Li Li, Junfang Hu and Yan Liu

    Citation: Infectious Agents and Cancer 2021 16:28

    Content type: Research Article

    Published on:

  19. Despite successful combined antiretroviral therapy (cART), the risk of non-AIDS defining cancers (NADCs) remains higher for HIV-infected individuals than the general population. The reason for this increase is...

    Authors: Christina K. S. Muller, Julian Spagnuolo, Annette Audigé, Andrew Chancellor, Doris Russenberger, Alexandra U. Scherrer, Matthias Hoffmann, Roger Kouyos, Manuel Battegay, Gennaro De Libero and Roberto F. Speck

    Citation: Infectious Agents and Cancer 2021 16:24

    Content type: Research Article

    Published on:

  20. The high-risk human papillomavirus (HPV) infection represents one of the main etiologic pathways of penile carcinogenesis in approximately 30–50 % of cases. Several techniques for the detection of HPV are curr...

    Authors: Federica Zito Marino, Rosalaura Sabetta, Francesca Pagliuca, Matteo Brunelli, Gabriella Aquino, Sisto Perdonà, Gerardo Botti, Gaetano Facchini, Francesco Fiorentino, Giovanni Di Lauro, Marco De Sio, Ferdinando De Vita, Giorgio Toni, Rodolfo Borges Dos Reis, Luciano Neder and Renato Franco

    Citation: Infectious Agents and Cancer 2021 16:22

    Content type: Research Article

    Published on:

    The Correction to this article has been published in Infectious Agents and Cancer 2021 16:23

  21. To assess the prevalence and distribution of HPV genotypes among Chinese Han women, and to explore the risk of high-grade cervical lesions associated with individual hr-HPV genotypes.

    Authors: Chunlei Guo, Hui Du, Jerome L. Belinson, Chun Wang, Xia Huang, Xinfeng Qu and Ruifang Wu

    Citation: Infectious Agents and Cancer 2021 16:21

    Content type: Research Article

    Published on:

  22. HBV promotes cell survival by upregulating the expression of the cellular inhibitor of apoptosis protein 2 (cIAP2), however whether it is involved in HBV-induced sorafenib resistance in liver cancer remains un...

    Authors: Shouhua Zhang, Nuoya Li, Yanling Sheng, Wen Chen, Qiangliang Ma, Xin Yu, Jianping Lian, Junquan Zeng, Yipeng Yang and Jinlong Yan

    Citation: Infectious Agents and Cancer 2021 16:20

    Content type: Research Article

    Published on:

  23. Biloma, an encapsulated collection of bile outside the biliary tree, supported by a predominantly iatrogenic biliary fistula, and bile likeage are two of the most important surgical complications after liver r...

    Authors: Renato Patrone, Vincenza Granata, Andrea Belli, Raffaele Palaia, Vittorio Albino, Mauro Piccirillo, Roberta Fusco, Fabiana Tatangelo, Guglielmo Nasti, Antonio Avallone and Francesco Izzo

    Citation: Infectious Agents and Cancer 2021 16:19

    Content type: Research Article

    Published on:

  24. Chronic Infection of Hepatitis B virus (HBV) is one risk factor of hepatocellular carcinoma (HCC). Much effort has been made to research the process of HBV-associated HCC, but its molecular mechanisms of carci...

    Authors: Chang Liu, Qinghai Dai, Qian Ding, Min Wei and Xiaohong Kong

    Citation: Infectious Agents and Cancer 2021 16:18

    Content type: Research Article

    Published on:

  25. The identification of effective prognosis biomarkers for nasopharyngeal carcinoma (NPC) is crucial to improve treatment and patient outcomes. In the present study, we have attempted to evaluate the correlation...

    Authors: Amina Gihbid, Raja Benzeid, Abdellah Faouzi, Jalal Nourlil, Nezha Tawfiq, Nadia Benchakroun, Amal Guensi, Karima Bendahhou, Abdellatif Benider, Naima El Benna, Imane Chaoui, Rachida Cadi, Mohammed El Mzibri and Meriem Khyatti

    Citation: Infectious Agents and Cancer 2021 16:15

    Content type: Research Article

    Published on:

  26. Frequent mutations in the nuclear receptor binding SET domain protein 1 (NSD1) gene have been observed in head and neck squamous cell carcinomas (HNSCC). NSD1 encodes a histone 3 lysine-36 methyltransferase. NSD1

    Authors: Steven F. Gameiro, Farhad Ghasemi, Peter Y. F. Zeng, Neil Mundi, Christopher J. Howlett, Paul Plantinga, John W. Barrett, Anthony C. Nichols and Joe S. Mymryk

    Citation: Infectious Agents and Cancer 2021 16:13

    Content type: Research Article

    Published on:

  27. Mucosa-associated lymphoid tissue (MALT) lymphoma is generally associated with chronic antigen stimulation: auto-antigens or of microbial origin. Only one study suggested association between Achromobacter xylosox...

    Authors: Raphaël Borie, Valérie Caro, Hilario Nunes, Marianne Kambouchner, Aurélie Cazes, Martine Antoine, Bruno Crestani, Karen Leroy, Christiane Copie-Bergman, Aurelia Kwasiborski, Christophe Hennequin, Mathias Vandenbogaert, Véronique Hourdel and Jacques Cadranel

    Citation: Infectious Agents and Cancer 2021 16:10

    Content type: Short Report

    Published on:

  28. The medical community has been deeply involved in fighting the Coronavirus disease 2019 (COVID-19) pandemic and, as a consequence, the care of non-COVID-19 patients has been impacted. However, the treatment of...

    Authors: Francesco Longo, Eleonora M. C. Trecca, Aurelio D’Ecclesia, Chiara Copelli, Karim Tewfik, Alfonso Manfuso, Nicola Pederneschi, Annalisa Mastromatteo, Matteo Aldo Russo, Antonio Pansini, Luca M. Lacerenza, Pier Gerardo Marano and Lazzaro Cassano

    Citation: Infectious Agents and Cancer 2021 16:9

    Content type: Review

    Published on:

  29. Human Cytomegalovirus (HCMV) is the most important viral pathogen in people undergoing bone marrow transplantation (BMT). HCMV detection in the early stages makes is possible to save the patients’ lives throug...

    Authors: Mehrdad Payandeh, Mohammad Hossein Zamanian, Bizhan Nomanpour, Mohammad Soroush Farhadi, Alireza Janbakhsh, Mosayeb Rostamian, Azam Elahi, Somayeh Jafari and Mohammad Dehghannejad

    Citation: Infectious Agents and Cancer 2021 16:8

    Content type: Research Article

    Published on:

  30. The etiology of prostate cancer (PCa) is multiple and complex. Among the causes recently cited are chronic infections engendered by microorganisms that often go unnoticed. A typical illustration of such a case...

    Authors: Osama Mohammed Saed Abdul-Wahab, Mishari H. Al-Shyarba, Boutheina Ben Abdelmoumen Mardassi, Nessrine Sassi, Majed Saad Shaya Al Fayi, Hassan Otifi, Abdullah Hassan Al Murea, Béhija Mlik and Elhem Yacoub

    Citation: Infectious Agents and Cancer 2021 16:6

    Content type: Research Article

    Published on:

  31. The aim was to evaluate the hepatitis C virus (HCV) cascade of care in the general population (GP) and in two high-risk populations: patients with diabetes mellitus (DM) and substance users (AS) in treatment i...

    Authors: Olivera Djuric, Marco Massari, Marta Ottone, Giorgia Collini, Pamela Mancuso, Massimo Vicentini, Antonio Nicolaci, Angela Zannini, Alessandro Zerbini, Valeria Manicardi, Loreta A. Kondili and Paolo Giorgi Rossi

    Citation: Infectious Agents and Cancer 2021 16:5

    Content type: Research Article

    Published on:

  32. COVID-19 has caused great concern for patients with underlying medical conditions. We aimed to determine the prognosis of patients with current or previous cancer with either a PCR-confirmed COVID-19 infection...

    Authors: Majid Sorouri, Amir Kasaeian, Helia Mojtabavi, Amir Reza Radmard, Shadi Kolahdoozan, Amir Anushiravani, Bardia Khosravi, Seyed Mohammad Pourabbas, Masoud Eslahi, Azin Sirusbakht, Marjan Khodabakhshi, Fatemeh Motamedi, Fatemeh Azizi, Reza Ghanbari, Zeynab Rajabi, Ali Reza Sima…

    Citation: Infectious Agents and Cancer 2020 15:74

    Content type: Research Article

    Published on:

  33. Coronavirus disease 19 (COVID-19) is an infection caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The pandemic spread of SARS-CoV-2 has resulted in significant health, economi...

    Authors: Christine Cassidy, Danielle Dever, Laura Stanbery, Gerald Edelman, Lance Dworkin and John Nemunaitis

    Citation: Infectious Agents and Cancer 2020 15:73

    Content type: Review

    Published on:

  34. The solid transport media is a small size card that allows fast, easy DNA extraction from a variety of biological samples. In 2016 we developed a solid media transport card; for that pilot study to control the...

    Authors: Hui Du, Xianzhi Duan, Yan Liu, Bin Shi, Wei Zhang, Chun Wang, Xinfen Qu, Juncui Bao, Jingran Li, Chao Zhao, Jing Jiang, Juan Liu, Kejia Wu, Aimin Xiao, Lvfang Duan, Xia Huang…

    Citation: Infectious Agents and Cancer 2020 15:72

    Content type: Research Article

    Published on:

  35. To explore the value of alpha fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) in diagnosis of HBV-related hepatocellular carcinoma (HCC) and their relationship with vascu...

    Authors: Yuan-Quan Si, Xiu-Qin Wang, Gang Fan, Chang-Yin Wang, Yuan-Wen Zheng, Xie Song, Cui-Cui Pan, Fu-Lu Chu, Zhan-Feng Liu, Bing-Ru Lu and Zhi-Ming Lu

    Citation: Infectious Agents and Cancer 2020 15:70

    Content type: Research Article

    Published on:

  36. This study was performed to evaluate the significance of positive resection margins (RMs) with the loop electrosurgical excision procedure combined with cold coagulation (LEEP with CC) as a definitive treatmen...

    Authors: Eun Jung Yang, Nae Ry Kim, Ji Yeon Choi, Wook Youn Kim and Sun Joo Lee

    Citation: Infectious Agents and Cancer 2020 15:58

    Content type: Research Article

    Published on:

  37. Hepatocellular carcinoma (HCC) is one of the cancers of highest incidence and mortality worldwide. The proliferation and invasion of tumor cells are the main reason for poor prognosis after HCC surgery. Long n...

    Authors: Quan Liu, Xuxu Yu, Minjie Yang, Xiangke Li, Xuejia Zhai, Yujin Lian, Zhong Chen, Qingxia Fan, Lijie Song and Wencai Li

    Citation: Infectious Agents and Cancer 2020 15:55

    Content type: Research Article

    Published on:

  38. Oral squamous cell carcinoma (OSCC) is the most common type of head and neck squamous cell carcinoma (HNSCC), and the effect of zymosan (ZYM), a component of the yeast cell wall, on oral cancer remains unclear...

    Authors: Xu Chen, Qingqiong Luo, Jieying Ding, Meng Yang, Ruiyang Zhang and Fuxiang Chen

    Citation: Infectious Agents and Cancer 2020 15:51

    Content type: Research Article

    Published on:

  39. Breast cancer is reported as one of the most common cancers among females worldwide. Infectious agents especially viruses have been considered as role players in the development of breast cancer. Although some...

    Authors: Alireza Khatami, Ali Pormohammad, Rana Farzi, Hassan Saadati, Maryam Mehrabi, Seyed Jalal Kiani and Saied Ghorbani

    Citation: Infectious Agents and Cancer 2020 15:48

    Content type: Review

    Published on:

  40. HPV causes specific cell-mediated immunity in the cervix. Mononuclear cells such as helper T cells (CD4+), cytotoxic T cells (CD8+), and dendritic cells play a critical role in the initiation of the HPV-specif...

    Authors: Ceyda Sancakli Usta, Eren Altun, Selim Afsar, Cagla Bahar Bulbul, Akin Usta and Ertan Adalı

    Citation: Infectious Agents and Cancer 2020 15:47

    Content type: Research Article

    Published on:

  41. Women living with human immunodeficiency virus (WLWH), especially those living in low- and middle-income countries (LMIC), are at increased risk of cervical cancer. The optimal cervical-cancer screening strate...

    Authors: Philip E. Castle, Rogers Ajeh, Anastase Dzudie, Ernestine Kendowo, Norbert Fuhngwa, Andre Gaetan Simo-Wambo, Denis Nsame, Enow Orock, Tiffany M. Hebert, Amanda J. Pierz, Daniel Murokora, Kathryn Anastos and Adebola Adedimeji

    Citation: Infectious Agents and Cancer 2020 15:45

    Content type: Short Report

    Published on:

  42. Sinonasal inverted papillomas (SIP) and sinonasal squamous cell carcinomas (SNSCC) are sinonasal tumors with unclear etiology and pathogenesis. Epstein-Barr virus (EBV) has been detected in these tumors but in...

    Authors: Thawaree Nukpook, Tipaya Ekalaksananan, Watchareporn Teeramatwanich, Natcha Patarapadungkit, Surachat Chaiwiriyakul, Patravoot Vatanasapt, Sirinart Aromseree and Chamsai Pientong

    Citation: Infectious Agents and Cancer 2020 15:43

    Content type: Research Article

    Published on:

  43. EBV produces miRNAs with important functions in cancer growth, tumor invasion and host immune surveillance. The discovery of EBV miR-BARTs is recent, and most of their functions are still unknown. Nonetheless,...

    Authors: Valli De Re, Laura Caggiari, Mariangela De Zorzi, Valentina Fanotto, Gianmaria Miolo, Fabio Puglisi, Renato Cannizzaro, Vincenzo Canzonieri, Agostino Steffan, Piero Farruggia, Egesta Lopci, Emanuele S. G. d’Amore, Roberta Burnelli, Lara Mussolin and Maurizio Mascarin

    Citation: Infectious Agents and Cancer 2020 15:42

    Content type: Review

    Published on:

  44. The anatomical complexity of the oropharynx and the difficulty in reaching its distal portion have always conditioned the surgical accessibility.

    Authors: Fraco Ionna, Agostino Guida, Luigi Califano, Gaetano Motta, Giovanni Salzano, Ettore Pavone, Corrado Aversa, Francesco Longo, Salvatore Villano, Ludovica Marcella Ponzo, Pierluigi Franco, Simona Losito, Franco Maria Buonaguro, Maria Lina Tornesello and Maria Grazia Maglione

    Citation: Infectious Agents and Cancer 2020 15:40

    Content type: Research Article

    Published on:

Annual Journal Metrics