From: Findings from a Malaysian multicentre study on oropharyngeal squamous cell carcinoma
Characteristics | HPV-associated OPSCC (n = 57) | HPV-independent OPSCC (n = 127) | p value | |
---|---|---|---|---|
Age Median [IQR] (Range) | 63.0 [11] (26–78) | 64.0 [15] (26–90) | 0.344Ϯ | |
Sex | Male | 46 | 94 | 0.356* |
Female | 11 | 33 | ||
Ethnicity | Malay | 12 | 27 |  < 0.001** |
Chinese | 31 | 32 | ||
Indian | 8 | 57 | ||
Others | 6 | 11 | ||
aHistory of tobacco use | No | 19 | 40 | 1.000* |
Yes (Current/Former) | 27 | 60 | ||
Not available | 11 | 27 | ||
aHistory of alcohol intake | No | 29 | 59 | 1.000* |
Yes (Current/Former) | 14 | 29 | ||
Not available | 14 | 39 | ||
aHistory of betel quid use | No | 35 | 59 |  < 0.001* |
Yes (Current/Former) | 0 | 23 | ||
Not available | 22 | 45 | ||
Site of tumour | Tonsil | 33 | 44 | 0.002** |
Base of tongue | 13 | 43 | ||
Soft palate & uvula | 9 | 15 | ||
Oropharynx Not Otherwise Specified (NOS) | 2 | 25 | ||
TNM staging Based on 7th edition of AJCC staging | Stage I | 0 | 3 | 0.789** |
Stage II | 3 | 8 | ||
Stage III | 11 | 22 | ||
Stage IVA | 31 | 58 | ||
Stage IVB | 7 | 18 | ||
Stage IVC | 5 | 18 |