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Table 1 Characteristics of 419 study participants by cervical intraepithelial neoplasia (CIN) status

From: Association between PEG3 DNA methylation and high-grade cervical intraepithelial neoplasia

Characteristic ≤CIN1
(n = 347)
n (%)
CIN2
(n = 52)
n (%)
CIN3+
(n = 20)
n (%)
p value
Age (median, IQR) 28.5 (11.5) 27.6 (11.6) 31.5 (15.1) .23
HPV infection     .07
 None 34 (9.8) 3 (5.8) 0 (0.0)  
 High-risk 246 (70.9) 44 (84.6) 19 (95.0)  
 Low-risk 67 (19.3) 5 (9.6) 1 (5.0)  
Ethnicity     .59
 Non-Hispanic Black 145 (41.8) 18 (34.6) 5 (25.0)  
 Non-Hispanic White 166 (47.8) 27 (51.9) 13 (65.0)  
 Hispanic 16 (4.6) 4 (7.7) 1 (5.0)  
 Othera 20 (5.8) 3 (5.8) 1 (5.0)  
Current cigarette smokingb     <.0001
 Yes 46 (13.3) 19 (36.5) 7 (35.0)  
 No 301 (86.7) 33 (63.5) 13 (65.0)  
Parityb     .003
 Nulliparous 186 (53.6) 18 (35.3) 6 (30.0)  
 Parous 161 (46.4) 33 (64.7) 14 (70.0)  
Hormonal contraceptive useb     .26
 Yes 260 (79.8) 35 (77.8) 13 (72.2)  
 No 66 (20.2) 10 (22.2) 5 (27.8)  
  1. Abbreviations: CIN Cervical intraepithelial neoplasia, IQR Interquartile range, HPV Human papillomavirus. High risk HPV - 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68
  2. Low risk HPV - 6, 11, 26, 40, 42, 53, 54, 55, 61, 62, 64, 69, 70, 72, 73, 81, 82, 83 and 84
  3. aOther includes Asian/Pacific Islanders and Native American
  4. bNumbers do not add up to the total due to missing values