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Table 1 Characteristics of 419 study participants by cervical intraepithelial neoplasia (CIN) status

From: Association between PEG3 DNA methylation and high-grade cervical intraepithelial neoplasia

Characteristic

≤CIN1

(n = 347)

n (%)

CIN2

(n = 52)

n (%)

CIN3+

(n = 20)

n (%)

p value

Age (median, IQR)

28.5 (11.5)

27.6 (11.6)

31.5 (15.1)

.23

HPV infection

   

.07

 None

34 (9.8)

3 (5.8)

0 (0.0)

 

 High-risk

246 (70.9)

44 (84.6)

19 (95.0)

 

 Low-risk

67 (19.3)

5 (9.6)

1 (5.0)

 

Ethnicity

   

.59

 Non-Hispanic Black

145 (41.8)

18 (34.6)

5 (25.0)

 

 Non-Hispanic White

166 (47.8)

27 (51.9)

13 (65.0)

 

 Hispanic

16 (4.6)

4 (7.7)

1 (5.0)

 

 Othera

20 (5.8)

3 (5.8)

1 (5.0)

 

Current cigarette smokingb

   

<.0001

 Yes

46 (13.3)

19 (36.5)

7 (35.0)

 

 No

301 (86.7)

33 (63.5)

13 (65.0)

 

Parityb

   

.003

 Nulliparous

186 (53.6)

18 (35.3)

6 (30.0)

 

 Parous

161 (46.4)

33 (64.7)

14 (70.0)

 

Hormonal contraceptive useb

   

.26

 Yes

260 (79.8)

35 (77.8)

13 (72.2)

 

 No

66 (20.2)

10 (22.2)

5 (27.8)

 
  1. Abbreviations: CIN Cervical intraepithelial neoplasia, IQR Interquartile range, HPV Human papillomavirus. High risk HPV - 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68
  2. Low risk HPV - 6, 11, 26, 40, 42, 53, 54, 55, 61, 62, 64, 69, 70, 72, 73, 81, 82, 83 and 84
  3. aOther includes Asian/Pacific Islanders and Native American
  4. bNumbers do not add up to the total due to missing values