Fig. 1
From: Hepatitis B virus induces sorafenib resistance in liver cancer via upregulation of cIAP2 expression
HBV infection induces resistance to sorafenib in liver cancer cells. a Liver cancer cell line HepG2 and HBV-transformed HepG2.215 cells were lysed and cIAP2 expression was determined by western blot. One representative data out of three is shown. b HepG2 and HepG2.215 cells were treated with ascendant doses of sorafenib for 24 h, and then cell viability was assessed by MTT. Data shown are mean ± SD of three independent experiments. *, p < 0.05; **, p < 0.01. c HepG2 and HepG2.215 cells were treated with ascendant doses of sorafenib for 24 h, and then cleaved caspase-3 was measured by western blot. One representative data out of three is shown