Oncogenic viruses associated with vulva cancer in HIV-1 patients in Botswana

Table 2 PCR summary of HIV-1 negative and positive vulva cancer samples

Negative	GP5+/6+	HPV-18	HPV-16	HPV-45	HPV-33	HPV-31	HPV-11	HPV-6	EBV	KSHV P1/P2	KSHV F/R	JC
1	+	-	-	-	-	-	-	-	+	-	-	-
2	+	-	+	+	-	+	-	+	+	-	-	-
3	-	-	+	-	-	+	-	+	+	-	-	-
4	+	-	+	+	-	+	-	-	+	-	-	-
5	+	-	+	+	-	+	-	-	+	+	-	-
6	+	-	+	+	-	+	+	-	+	-	-	-
7	+	-	+	+	-	-	-	-	+	-	-	-
8	-	-	-	-	-	-	-	+	-	-	-	-
9	-	-	+	-	-	+	-	+	+	-	-	-
Total	67%		78%	56%		67%	11%	44%	89%	11%
Positive
1	+	-	+	-	-	+	-	+	+	+	+	-
2	+	-	+	-	-	+	-	+	+	+	+	-
3	+	-	+	+	+	+	-	+	+	-	+	-
4	+	-	+	-	-	+	-	+	+	-	-	-
5	+	+	+	+	-	+	-	-	+	-	+	-
6	-	-	-	-	-	-	-	+	+	+	+	-
7	-	-	-	-	-	-	+	+	+	-	-	-
8	-	-	+	-	-	+	-	-	+	-	-	-
9	-	-	+	+	-	+	+	-	+	-	-	-
10	+	-	+	-	-	+	+	-	+	+	-	-
11	-	-	-	-	-	+	-	-	+	+	-	-
12	+	-	+	+	-	+	-	-	+	-	-	-
13	-	-	+	+	-	+	-	-	+	-	-	-
Total	54%	8%	77%	39%	8%	85%	23%	46%	100%	39%	39%
OR	0.57	18.47	0.94	0.50	18.47	1.94	2.41	1.08	25.82	5.17	129.09	NA
CI	0.32-1.02	1.05-324.5	0.48-1.83	0.28- 0.88	1.05- 324	0.94-4.01	1.10-5.27	0.62-1.89	1.50-444.6	2.45-10.8	7.7-2138.5	NA
P Value	0.06	0.04	0.86	0.01	0.04	0.07	0.02	0.78	0.02	<0.01	<0.01	NA

Oncogenic viruses identified in each VSCC patient as determined by PCR analysis. Most cases tested positive for HPV, EBV, KSHV, and HSV in HIV-1 positive and negative samples. None was positive for JC virus.

ISSN: 1750-9378